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Hybridization kinetics between immobilized double-stranded DNA probes and targets containing embedded recognition segments

We have investigated the time-dependent strand displacement activity of several targets with double-stranded DNA probes (dsProbes) of varying affinity. Here, the relative affinity of various dsProbes is altered through choices in hybridization length (11–15 bases) and the selective inclusion of cent...

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Detalles Bibliográficos
Autores principales: Baker, Bryan A., Milam, Valeria T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159461/
https://www.ncbi.nlm.nih.gov/pubmed/21613238
http://dx.doi.org/10.1093/nar/gkr293