Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques

Homologous recombination is essential for the preservation of genome stability, thereby preventing cancer. The recombination protein RAD51 drives DNA strand exchange, which requires the assembly, rearrangement and disassembly of a RAD51 filament on DNA, coupled to ATP binding and hydrolysis. This pr...

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Detalles Bibliográficos
Autores principales: Holthausen, J. T., van Loenhout, M. T. J., Sanchez, H., Ristic, D., van Rossum-Fikkert, S. E., Modesti, M., Dekker, C., Kanaar, R., Wyman, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159462/
https://www.ncbi.nlm.nih.gov/pubmed/21576230
http://dx.doi.org/10.1093/nar/gkr295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159462/
https://www.ncbi.nlm.nih.gov/pubmed/21576230
http://dx.doi.org/10.1093/nar/gkr295

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