High-resolution analysis of four efficient yeast replication origins reveals new insights into the ORC and putative MCM binding elements

In budding yeast, the eukaryotic initiator protein ORC (origin recognition complex) binds to a bipartite sequence consisting of an 11 bp ACS element and an adjacent B1 element. However, the genome contains many more matches to this consensus than actually bind ORC or function as origins in vivo. Alt...

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Detalles Bibliográficos
Autores principales: Chang, FuJung, May, Caitlin D., Hoggard, Timothy, Miller, Jeremy, Fox, Catherine A., Weinreich, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159467/
https://www.ncbi.nlm.nih.gov/pubmed/21558171
http://dx.doi.org/10.1093/nar/gkr301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159467/
https://www.ncbi.nlm.nih.gov/pubmed/21558171
http://dx.doi.org/10.1093/nar/gkr301

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