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High-resolution analysis of four efficient yeast replication origins reveals new insights into the ORC and putative MCM binding elements
In budding yeast, the eukaryotic initiator protein ORC (origin recognition complex) binds to a bipartite sequence consisting of an 11 bp ACS element and an adjacent B1 element. However, the genome contains many more matches to this consensus than actually bind ORC or function as origins in vivo. Alt...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159467/ https://www.ncbi.nlm.nih.gov/pubmed/21558171 http://dx.doi.org/10.1093/nar/gkr301 |