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A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines

SnowShoes-FTD, developed for fusion transcript detection in paired-end mRNA-Seq data, employs multiple steps of false positive filtering to nominate fusion transcripts with near 100% confidence. Unique features include: (i) identification of multiple fusion isoforms from two gene partners; (ii) pred...

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Detalles Bibliográficos
Autores principales: Asmann, Yan W., Hossain, Asif, Necela, Brian M., Middha, Sumit, Kalari, Krishna R., Sun, Zhifu, Chai, High-Seng, Williamson, David W., Radisky, Derek, Schroth, Gary P., Kocher, Jean-Pierre A., Perez, Edith A., Thompson, E. Aubrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159479/
https://www.ncbi.nlm.nih.gov/pubmed/21622959
http://dx.doi.org/10.1093/nar/gkr362