High-level transgene expression by homologous recombination-mediated gene transfer

Gene transfer and expression in eukaryotes is often limited by a number of stably maintained gene copies and by epigenetic silencing effects. Silencing may be limited by the use of epigenetic regulatory sequences such as matrix attachment regions (MAR). Here, we show that successive transfections of...

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Detalles Bibliográficos
Autores principales: Grandjean, Mélanie, Girod, Pierre-Alain, Calabrese, David, Kostyrko, Kaja, Wicht, Marianne, Yerly, Florence, Mazza, Christian, Beckmann, Jacques S., Martinet, Danielle, Mermod, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159483/
https://www.ncbi.nlm.nih.gov/pubmed/21652640
http://dx.doi.org/10.1093/nar/gkr436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159483/
https://www.ncbi.nlm.nih.gov/pubmed/21652640
http://dx.doi.org/10.1093/nar/gkr436

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