Signaling role for Mg(2+) revealed by immunodeficiency due to loss of MagT1

The magnesium ion, Mg(2+), is essential for all life as a cofactor for ATP, polyphosphates such as DNA and RNA, and metabolic enzymes, but whether it plays a role in intracellular signaling similar to Ca(2+) is unknown. In this study, we identify mutations in the magnesium transporter gene, MAGT1, i...

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Detalles Bibliográficos
Autores principales: Li, Feng-Yen, Chaigne-Delalande, Benjamin, Kanellopoulou, Chrysi, Davis, Jeremiah C., Matthews, Helen F., Douek, Daniel C., Cohen, Jeffrey I., Uzel, Gulbu, Su, Helen C., Lenardo, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159560/
https://www.ncbi.nlm.nih.gov/pubmed/21796205
http://dx.doi.org/10.1038/nature10246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159560/
https://www.ncbi.nlm.nih.gov/pubmed/21796205
http://dx.doi.org/10.1038/nature10246

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