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Pharmacokinetics of pirfenidone after topical administration in rabbit eye

PURPOSE: Pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone) is a new, broad-spectrum agent that has an inhibition effect on the proliferation, migration, and collagen contraction of human Tenon’s fibroblasts, and thus modulating the wound healing process of glaucoma filtering surgical site. This study...

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Detalles Bibliográficos
Autores principales: Sun, Guoying, Lin, Xianchai, Zhong, Hua, Yang, Yangfan, Qiu, Xuan, Ye, Chengtian, Wu, Kaili, Yu, Minbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159682/
https://www.ncbi.nlm.nih.gov/pubmed/21866212