Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling

FoxO transcription factors, inhibited by insulin/insulin-like growth factor signalling (IIS), are crucial players in numerous organismal processes including lifespan. Using genomic tools, we uncover over 700 direct dFOXO targets in adult female Drosophila. dFOXO is directly required for transcriptio...

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Detalles Bibliográficos
Autores principales: Alic, Nazif, Andrews, T Daniel, Giannakou, Maria E, Papatheodorou, Irene, Slack, Cathy, Hoddinott, Matthew P, Cochemé, Helena M, Schuster, Eugene F, Thornton, Janet M, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159968/
https://www.ncbi.nlm.nih.gov/pubmed/21694719
http://dx.doi.org/10.1038/msb.2011.36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159968/
https://www.ncbi.nlm.nih.gov/pubmed/21694719
http://dx.doi.org/10.1038/msb.2011.36

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