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Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range
Cellular signal transduction is governed by multiple feedback mechanisms to elicit robust cellular decisions. The specific contributions of individual feedback regulators, however, remain unclear. Based on extensive time-resolved data sets in primary erythroid progenitor cells, we established a dyna...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159971/ https://www.ncbi.nlm.nih.gov/pubmed/21772264 http://dx.doi.org/10.1038/msb.2011.50 |