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Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range

Cellular signal transduction is governed by multiple feedback mechanisms to elicit robust cellular decisions. The specific contributions of individual feedback regulators, however, remain unclear. Based on extensive time-resolved data sets in primary erythroid progenitor cells, we established a dyna...

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Detalles Bibliográficos
Autores principales:	Bachmann, Julie, Raue, Andreas, Schilling, Marcel, Böhm, Martin E, Kreutz, Clemens, Kaschek, Daniel, Busch, Hauke, Gretz, Norbert, Lehmann, Wolf D, Timmer, Jens, Klingmüller, Ursula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Molecular Biology Organization 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159971/ https://www.ncbi.nlm.nih.gov/pubmed/21772264 http://dx.doi.org/10.1038/msb.2011.50

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