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A dynamic model of proteome changes reveals new roles for transcript alteration in yeast

The transcriptome and proteome change dynamically as cells respond to environmental stress; however, prior proteomic studies reported poor correlation between mRNA and protein, rendering their relationships unclear. To address this, we combined high mass accuracy mass spectrometry with isobaric tagg...

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Detalles Bibliográficos
Autores principales: Lee, M Violet, Topper, Scott E, Hubler, Shane L, Hose, James, Wenger, Craig D, Coon, Joshua J, Gasch, Audrey P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159980/
https://www.ncbi.nlm.nih.gov/pubmed/21772262
http://dx.doi.org/10.1038/msb.2011.48