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The Construction of Chimeric T-Cell Receptor with Spacer Base of Modeling Study of VHH and MUC1 Interaction

Adaptive cell immunotherapy with the use of chimeric receptors leads to the best and most specific response against tumors. Chimeric receptors consist of a signaling fragment, extracellular spacer, costimulating domain, and an antibody. Antibodies cause immunogenicity; therefore, VHH is a good repla...

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Detalles Bibliográficos
Autores principales: Pirooznia, Nazanin, Hasannia, Sadegh, Taghdir, Majid, Rahbarizadeh, Fatemeh, Eskandani, Morteza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160013/
https://www.ncbi.nlm.nih.gov/pubmed/21869862
http://dx.doi.org/10.1155/2011/578128