HIV-1 Nef Induces Proinflammatory State in Macrophages through Its Acidic Cluster Domain: Involvement of TNF Alpha Receptor Associated Factor 2

BACKGROUND: HIV-1 Nef is a virulence factor that plays multiple roles during HIV replication. Recently, it has been described that Nef intersects the CD40 signalling in macrophages, leading to modification in the pattern of secreted factors that appear able to recruit, activate and render T lymphocy...

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Detalles Bibliográficos
Autores principales: Mangino, Giorgio, Percario, Zulema A., Fiorucci, Gianna, Vaccari, Gabriele, Acconcia, Filippo, Chiarabelli, Cristiano, Leone, Stefano, Noto, Alessia, Horenkamp, Florian A., Manrique, Santiago, Romeo, Giovanna, Polticelli, Fabio, Geyer, Matthias, Affabris, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160284/
https://www.ncbi.nlm.nih.gov/pubmed/21886773
http://dx.doi.org/10.1371/journal.pone.0022982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160284/
https://www.ncbi.nlm.nih.gov/pubmed/21886773
http://dx.doi.org/10.1371/journal.pone.0022982

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