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Mannosidase 2, alpha 1 Deficiency Is Associated with Ricin Resistance in Embryonic Stem (ES) Cells

Host gene products required for mediating the action of toxins are potential targets for reversing or controlling their pathogenic impact following exposure. To identify such targets libraries of insertional gene-trap mutations generated with a PiggyBac transposon in Blm-deficient embryonic stem cel...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Hale, Christine, Goulding, Dave, Haslam, Stuart M., Tissot, Bérangère, Lindsay, Christopher, Michell, Stephen, Titball, Rick, Yu, Jun, Toribio, Ana Luisa, Rossi, Raffaella, Dell, Anne, Bradley, Allan, Dougan, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160287/
https://www.ncbi.nlm.nih.gov/pubmed/21886775
http://dx.doi.org/10.1371/journal.pone.0022993