Cargando…

P38 Mitogen-Activated Protein Kinase Inhibitor, FR167653, Inhibits Parathyroid Hormone Related Protein-Induced Osteoclastogenesis and Bone Resorption

p38 mitogen-activated protein kinase (MAPK) acts downstream in the signaling pathway that includes receptor activator of NF-κB (RANK), a powerful inducer of osteoclast formation and activation. We investigated the role of p38 MAPK in parathyroid hormone related protein (PTHrP)-induced osteoclastogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Tao, Huiren, Okamoto, Mina, Nishikawa, Masataka, Yoshikawa, Hideki, Myoui, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160289/
https://www.ncbi.nlm.nih.gov/pubmed/21886782
http://dx.doi.org/10.1371/journal.pone.0023199