Metastasis of Tumor Cells Is Enhanced by Downregulation of Bit1

BACKGROUND: Resistance to anoikis, which is defined as apoptosis induced by loss of integrin-mediated cell attachment to the extracellular matrix, is a determinant of tumor progression and metastasis. We have previously identified the mitochondrial Bit1 (Bcl-2 inhibitor of transcription) protein as...

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Detalles Bibliográficos
Autores principales: Karmali, Priya Prakash, Brunquell, Chris, Tram, Hau, Ireland, Shubha Kale, Ruoslahti, Erkki, Biliran, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160313/
https://www.ncbi.nlm.nih.gov/pubmed/21886829
http://dx.doi.org/10.1371/journal.pone.0023840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160313/
https://www.ncbi.nlm.nih.gov/pubmed/21886829
http://dx.doi.org/10.1371/journal.pone.0023840

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