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An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV(1): a longitudinal retrospective cohort study
BACKGROUND: An Nrf2-dependent response is a central protective mechanism against oxidative stress. We propose that particular genetic variants of the Nrf2 gene may be associated with a rapid forced expiratory volume in one second (FEV(1)) decline induced by cigarette smoking. METHODS: We conducted a...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160350/ https://www.ncbi.nlm.nih.gov/pubmed/21774808 http://dx.doi.org/10.1186/1471-2350-12-97 |