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Integration of Genome-Wide Computation DRE Search, AhR ChIP-chip and Gene Expression Analyses of TCDD-Elicited Responses in the Mouse Liver

BACKGROUND: The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor (TF) that mediates responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Integration of TCDD-induced genome-wide AhR enrichment, differential gene expression and computational dioxin response element (DRE)...

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Detalles Bibliográficos
Autores principales: Dere, Edward, Lo, Raymond, Celius, Trine, Matthews, Jason, Zacharewski, Timothy R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160422/
https://www.ncbi.nlm.nih.gov/pubmed/21762485
http://dx.doi.org/10.1186/1471-2164-12-365