Native N-glycopeptide thioester synthesis through N→S acyl transfer

Peptide thioesters are important tools for the total synthesis of proteins using native chemical ligation (NCL). Preparation of glycopeptide thioesters, that enable the assembly of homogeneously glycosylated proteins, is complicated by the perceived fragile nature of the sugar moiety. Herein, we dem...

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Detalles Bibliográficos
Autores principales: Premdjee, Bhavesh, Adams, Anna L., Macmillan, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160546/
https://www.ncbi.nlm.nih.gov/pubmed/21676613
http://dx.doi.org/10.1016/j.bmcl.2011.05.059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160546/
https://www.ncbi.nlm.nih.gov/pubmed/21676613
http://dx.doi.org/10.1016/j.bmcl.2011.05.059

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