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Aurora B dynamics at centromeres create a diffusion-based phosphorylation gradient

Aurora B kinase is essential for successful cell division and regulates spindle assembly and kinetochore–microtubule interactions. The kinase localizes to the inner centromere until anaphase, but many of its substrates have distinct localizations, for example on chromosome arms and at kinetochores....

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Detalles Bibliográficos
Autores principales: Wang, Enxiu, Ballister, Edward R., Lampson, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160582/
https://www.ncbi.nlm.nih.gov/pubmed/21844210
http://dx.doi.org/10.1083/jcb.201103044