Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability

RanBP2/Nup358, the major component of the cytoplasmic filaments of the nuclear pore complex (NPC), is essential for mouse embryogenesis and is implicated in both macromolecular transport and mitosis, but its specific molecular functions are unknown. Using RanBP2 conditional knockout mouse embryonic...

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Detalles Bibliográficos
Autores principales: Hamada, Masakazu, Haeger, Anna, Jeganathan, Karthik B., van Ree, Janine H., Malureanu, Liviu, Wälde, Sarah, Joseph, Jomon, Kehlenbach, Ralph H., van Deursen, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160583/
https://www.ncbi.nlm.nih.gov/pubmed/21859863
http://dx.doi.org/10.1083/jcb.201102018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160583/
https://www.ncbi.nlm.nih.gov/pubmed/21859863
http://dx.doi.org/10.1083/jcb.201102018

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