Cargando…

PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution

Centromeres nucleate the formation of kinetochores and are vital for chromosome segregation during mitosis. The SNF2 family helicase PICH (Plk1-interacting checkpoint helicase) and the BLM (the Bloom's syndrome protein) helicase decorate ultrafine histone-negative DNA threads that link the segr...

Descripción completa

Detalles Bibliográficos
Autores principales: Ke, Yuwen, Huh, Jae-Wan, Warrington, Ross, Li, Bing, Wu, Nan, Leng, Mei, Zhang, Junmei, Ball, Haydn L, Yu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160651/
https://www.ncbi.nlm.nih.gov/pubmed/21743438
http://dx.doi.org/10.1038/emboj.2011.226