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A Peptide Mimetic Targeting Trans-Homophilic NCAM Binding Sites Promotes Spatial Learning and Neural Plasticity in the Hippocampus

The key roles played by the neural cell adhesion molecule (NCAM) in plasticity and cognition underscore this membrane protein as a relevant target to develop cognitive-enhancing drugs. However, NCAM is a structurally and functionally complex molecule with multiple domains engaged in a variety of act...

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Detalles Bibliográficos
Autores principales: Kraev, Igor, Henneberger, Christian, Rossetti, Clara, Conboy, Lisa, Kohler, Lene B., Fantin, Martina, Jennings, Alistair, Venero, Cesar, Popov, Victor, Rusakov, Dmitri, Stewart, Michael G., Bock, Elisabeth, Berezin, Vladimir, Sandi, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160849/
https://www.ncbi.nlm.nih.gov/pubmed/21887252
http://dx.doi.org/10.1371/journal.pone.0023433