Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies

Fexofenadine (FEX) has high solubility and low permeability (BCS, Class III). In this work, novel FEX loaded water in oil microemulsion (w/o) was designed to improve bioavailability and compared with Fexofen(®) syrup in in vitro and in vivo studies. In addition, pharmacokinetic parameters in permeab...

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Detalles Bibliográficos
Autores principales: Gundogdu, E, Alvarez, I Gonzalez, Karasulu, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160949/
https://www.ncbi.nlm.nih.gov/pubmed/21904453
http://dx.doi.org/10.2147/IJN.S22673

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160949/
https://www.ncbi.nlm.nih.gov/pubmed/21904453
http://dx.doi.org/10.2147/IJN.S22673

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