Development of small interfering RNA delivery system using PEI-PEG-APRPG polymer for antiangiogenic vascular endothelial growth factor tumor-targeted therapy

BACKGROUND: Small interfering RNA (siRNA) can silence target genes in the cytoplasm and be a major tool in gene therapy. Vascular endothelial growth factor (VEGF), a potent regulator of angiogenesis, is overexpressed in most tumors and is closely associated with tumor growth and metastasis. It has b...

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Detalles Bibliográficos
Autores principales: Lu, Zong-Xia, Liu, Li-Ting, Qi, Xian-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160952/
https://www.ncbi.nlm.nih.gov/pubmed/21904456
http://dx.doi.org/10.2147/IJN.S22293

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160952/
https://www.ncbi.nlm.nih.gov/pubmed/21904456
http://dx.doi.org/10.2147/IJN.S22293

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