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QTLRel: an R Package for Genome-wide Association Studies in which Relatedness is a Concern

BACKGROUND: Existing software for quantitative trait mapping is either not able to model polygenic variation or does not allow incorporation of more than one genetic variance component. Improperly modeling the genetic relatedness among subjects can result in excessive false positives. We have develo...

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Detalles Bibliográficos
Autores principales: Cheng, Riyan, Abney, Mark, Palmer, Abraham A, Skol, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160955/
https://www.ncbi.nlm.nih.gov/pubmed/21794153
http://dx.doi.org/10.1186/1471-2156-12-66