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QTLRel: an R Package for Genome-wide Association Studies in which Relatedness is a Concern
BACKGROUND: Existing software for quantitative trait mapping is either not able to model polygenic variation or does not allow incorporation of more than one genetic variance component. Improperly modeling the genetic relatedness among subjects can result in excessive false positives. We have develo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160955/ https://www.ncbi.nlm.nih.gov/pubmed/21794153 http://dx.doi.org/10.1186/1471-2156-12-66 |