Pharmacogenetic Associations of MMP9 and MMP12 Variants with Cardiovascular Disease in Patients with Hypertension

OBJECTIVES: MMP-9 and -12 function in tissue remodeling and may play roles in cardiovascular disease (CVD). We assessed associations of four MMP polymorphisms and three antihypertensive drugs with cardiovascular outcomes. METHODS: Hypertensives (n = 42,418) from a double-blind, randomized, clinical...

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Detalles Bibliográficos
Autores principales: Tanner, Rikki M., Lynch, Amy I., Brophy, Victoria H., Eckfeldt, John H., Davis, Barry R., Ford, Charles E., Boerwinkle, Eric, Arnett, Donna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160956/
https://www.ncbi.nlm.nih.gov/pubmed/21887284
http://dx.doi.org/10.1371/journal.pone.0023609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160956/
https://www.ncbi.nlm.nih.gov/pubmed/21887284
http://dx.doi.org/10.1371/journal.pone.0023609

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