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Grape seed proanthocyanidin extract inhibits glutamate-induced cell death through inhibition of calcium signals and nitric oxide formation in cultured rat hippocampal neurons
BACKGROUND: Proanthocyanidin is a polyphenolic bioflavonoid with known antioxidant activity. Some flavonoids have a modulatory effect on [Ca(2+)](i). Although proanthocyanidin extract from blueberries reportedly affects Ca(2+ )buffering capacity, there are no reports on the effects of proanthocyanid...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160962/ https://www.ncbi.nlm.nih.gov/pubmed/21810275 http://dx.doi.org/10.1186/1471-2202-12-78 |