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Cyclic AMP induces apoptosis in multiple myeloma cells and inhibits tumor development in a mouse myeloma model

BACKGROUND: Multiple myeloma is an incurable disease requiring the development of effective therapies which can be used clinically. We have elucidated the potential for manipulating the cAMP signaling pathway as a target for inhibiting the growth of multiple myeloma cells. METHODS: As a model system...

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Detalles Bibliográficos
Autores principales: Follin-Arbelet, Virginie, Hofgaard, Peter O, Hauglin, Harald, Naderi, Soheil, Sundan, Anders, Blomhoff, Rune, Bogen, Bjarne, Blomhoff, Heidi K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161033/
https://www.ncbi.nlm.nih.gov/pubmed/21767374
http://dx.doi.org/10.1186/1471-2407-11-301