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Efficient Detection of Proteins Retro-Translocated from the ER to the Cytosol by In Vivo Biotinylation
Retro-translocation from the ER to the cytosol of proteins within the secretory pathway takes place on misfolded molecules that are targeted for degradation by the cytosolically located 26S proteasome complex. Retro-translocation occurs also for other proteins (such as calreticulin) that, despite be...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161056/ https://www.ncbi.nlm.nih.gov/pubmed/21887304 http://dx.doi.org/10.1371/journal.pone.0023712 |