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Efficient Detection of Proteins Retro-Translocated from the ER to the Cytosol by In Vivo Biotinylation

Retro-translocation from the ER to the cytosol of proteins within the secretory pathway takes place on misfolded molecules that are targeted for degradation by the cytosolically located 26S proteasome complex. Retro-translocation occurs also for other proteins (such as calreticulin) that, despite be...

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Detalles Bibliográficos
Autores principales: Petris, Gianluca, Vecchi, Lara, Bestagno, Marco, Burrone, Oscar R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161056/
https://www.ncbi.nlm.nih.gov/pubmed/21887304
http://dx.doi.org/10.1371/journal.pone.0023712