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Identification and Characterization of Alternative Promoters, Transcripts and Protein Isoforms of Zebrafish R2 Gene

Ribonucleotide reductase (RNR) is the rate-limiting enzyme in the de novo synthesis of deoxyribonucleoside triphosphates. Expression of RNR subunits is closely associated with DNA replication and repair. Mammalian RNR M2 subunit (R2) functions exclusively in DNA replication of normal cells due to it...

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Detalles Bibliográficos
Autores principales: Shang, Hanqiao, Li, Qing, Feng, Guohui, Cui, Zongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161108/
https://www.ncbi.nlm.nih.gov/pubmed/21887375
http://dx.doi.org/10.1371/journal.pone.0024089