Aging mice have increased chromosome instability that is exacerbated by elevated Mdm2 expression

Aging is thought to negatively affect multiple cellular processes, including the ability to maintain chromosome stability. Chromosome instability (CIN) is a common property of cancer cells and may be a contributing factor to cellular transformation. The types of DNA aberrations that arise during agi...

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Detalles Bibliográficos
Autores principales: Lushnikova, Tamara, Bouska, Alyssa, Odvody, Jessica, Dupont, William D., Eischen, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161162/
https://www.ncbi.nlm.nih.gov/pubmed/21602883
http://dx.doi.org/10.1038/onc.2011.172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161162/
https://www.ncbi.nlm.nih.gov/pubmed/21602883
http://dx.doi.org/10.1038/onc.2011.172

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