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The exonuclease activity of hPMC2 is required for transcriptional regulation of the QR gene and repair of estrogen-induced abasic sites

We have previously reported that the expression of antioxidative stress enzymes are upregulated by trans-hydroxytamoxifen (TOT) in breast epithelial cell lines providing protection against estrogen-induced DNA damage. This regulation involves Estrogen Receptor beta (ERβ) recruitment to the Electroph...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Nirmala, Ngam, Caitlyn R., Berdis, Anthony J., Montano, Monica M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161170/
https://www.ncbi.nlm.nih.gov/pubmed/21602889
http://dx.doi.org/10.1038/onc.2011.186