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Apolipoprotein E4 Exaggerates Diabetic Dyslipidemia and Atherosclerosis in Mice Lacking the LDL Receptor

OBJECTIVE: We investigated the differential roles of apolipoprotein E (apoE) isoforms in modulating diabetic dyslipidemia—a potential cause of the increased cardiovascular disease risk of patients with diabetes. RESEARCH DESIGN AND METHODS: Diabetes was induced using streptozotocin (STZ) in human ap...

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Detalles Bibliográficos
Autores principales: Johnson, Lance A., Arbones-Mainar, Jose M., Fox, Raymond G., Pendse, Avani A., Altenburg, Michael K., Kim, Hyung-Suk, Maeda, Nobuyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161311/
https://www.ncbi.nlm.nih.gov/pubmed/21810592
http://dx.doi.org/10.2337/db11-0466