Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

OBJECTIVE: The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyssenko, Valeriya, Eliasson, Lena, Kotova, Olga, Pilgaard, Kasper, Wierup, Nils, Salehi, Albert, Wendt, Anna, Jonsson, Anna, De Marinis, Yang Z., Berglund, Lisa M., Taneera, Jalal, Balhuizen, Alexander, Hansson, Ola, Osmark, Peter, Dunér, Pontus, Brøns, Charlotte, Stančáková, Alena, Kuusisto, Johanna, Bugliani, Marco, Saxena, Richa, Ahlqvist, Emma, Kieffer, Timothy J., Tuomi, Tiinamaija, Isomaa, Bo, Melander, Olle, Sonestedt, Emily, Orho-Melander, Marju, Nilsson, Peter, Bonetti, Sara, Bonadonna, Riccardo, Miccoli, Roberto, DelPrato, Stefano, Marchetti, Piero, Madsbad, Sten, Poulsen, Pernille, Vaag, Allan, Laakso, Markku, Gomez, Maria F., Groop, Leif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161325/
https://www.ncbi.nlm.nih.gov/pubmed/21810601
http://dx.doi.org/10.2337/db10-1532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161325/
https://www.ncbi.nlm.nih.gov/pubmed/21810601
http://dx.doi.org/10.2337/db10-1532

Ejemplares similares