Dual targeting of CCR2 and CX3CR1 in an arterial injury model of vascular inflammation

OBJECTIVES: The chemokine receptors CCR2 and CX3CR1 are important in the development of coronary artery disease. The purpose of this study is to analyze the effect of a novel CCR2 inhibitor in conjunction with CX3CR1 deletion on vascular inflammation. METHODS: The novel CCR2 antagonist MRL-677 was c...

Descripción completa

Detalles Bibliográficos
Autores principales: Jerath, Maya R, Liu, Peng, Struthers, Mary, DeMartino, Julie A, Peng, Roche, Peterson, Laurence B, Cumiskey, Anne-Marie, Yang, Lihu, Rojas, Mauricio, Patel, Dhavalkumar D, Fong, Alan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Original Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161339/
https://www.ncbi.nlm.nih.gov/pubmed/20836883
http://dx.doi.org/10.1186/1477-9560-8-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161339/
https://www.ncbi.nlm.nih.gov/pubmed/20836883
http://dx.doi.org/10.1186/1477-9560-8-14

Ejemplares similares