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Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration

BACKGROUND: Type 2 diabetes mellitus (T2DM) and several types of neurodegeneration, including Alzheimer's, are linked to insulin-resistance, and chronic high dietary fat intake causes T2DM with mild neurodegeneration. Intra-cerebral Streptozotocin, a nitrosamine-related compound, causes neurode...

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Detalles Bibliográficos
Autores principales: Tong, Ming, Longato, Lisa, de la Monte, Suzanne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161394/
https://www.ncbi.nlm.nih.gov/pubmed/20302640
http://dx.doi.org/10.1186/1472-6823-10-4