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Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration
BACKGROUND: Type 2 diabetes mellitus (T2DM) and several types of neurodegeneration, including Alzheimer's, are linked to insulin-resistance, and chronic high dietary fat intake causes T2DM with mild neurodegeneration. Intra-cerebral Streptozotocin, a nitrosamine-related compound, causes neurode...
Autores principales: | Tong, Ming, Longato, Lisa, de la Monte, Suzanne M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161394/ https://www.ncbi.nlm.nih.gov/pubmed/20302640 http://dx.doi.org/10.1186/1472-6823-10-4 |
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