Modulation of Toxin Stability by 4-Phenylbutyric Acid and Negatively Charged Phospholipids

AB toxins such as ricin and cholera toxin (CT) consist of an enzymatic A domain and a receptor-binding B domain. After endocytosis of the surface-bound toxin, both ricin and CT are transported by vesicle carriers to the endoplasmic reticulum (ER). The A subunit then dissociates from its holotoxin, u...

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Detalles Bibliográficos
Autores principales: Ray, Supriyo, Taylor, Michael, Burlingame, Mansfield, Tatulian, Suren A., Teter, Ken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161752/
https://www.ncbi.nlm.nih.gov/pubmed/21887297
http://dx.doi.org/10.1371/journal.pone.0023692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161752/
https://www.ncbi.nlm.nih.gov/pubmed/21887297
http://dx.doi.org/10.1371/journal.pone.0023692

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