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Modulation of Toxin Stability by 4-Phenylbutyric Acid and Negatively Charged Phospholipids
AB toxins such as ricin and cholera toxin (CT) consist of an enzymatic A domain and a receptor-binding B domain. After endocytosis of the surface-bound toxin, both ricin and CT are transported by vesicle carriers to the endoplasmic reticulum (ER). The A subunit then dissociates from its holotoxin, u...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161752/ https://www.ncbi.nlm.nih.gov/pubmed/21887297 http://dx.doi.org/10.1371/journal.pone.0023692 |