Influenza-Specific T Cells from Older People Are Enriched in the Late Effector Subset and Their Presence Inversely Correlates with Vaccine Response

T cells specific for persistent pathogens accumulate with age and express markers of immune senescence. In contrast, much less is known about the state of T cell memory for acutely infecting pathogens. Here we examined T cell responses to influenza in human peripheral blood mononuclear cells from ol...

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Detalles Bibliográficos
Autores principales: Wagar, Lisa E., Gentleman, Beth, Pircher, Hanspeter, McElhaney, Janet E., Watts, Tania H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161762/
https://www.ncbi.nlm.nih.gov/pubmed/21887299
http://dx.doi.org/10.1371/journal.pone.0023698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161762/
https://www.ncbi.nlm.nih.gov/pubmed/21887299
http://dx.doi.org/10.1371/journal.pone.0023698

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