Divalent Metal Ion Differentially Regulates the Sequential Nicking Reactions of the GIY-YIG Homing Endonuclease I-BmoI

Homing endonucleases are site-specific DNA endonucleases that function as mobile genetic elements by introducing double-strand breaks or nicks at defined locations. Of the major families of homing endonucleases, the modular GIY-YIG endonucleases are least understood in terms of mechanism. The GIY-YI...

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Detalles Bibliográficos
Autores principales: Kleinstiver, Benjamin P., Bérubé-Janzen, Wesley, Fernandes, Andrew D., Edgell, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161791/
https://www.ncbi.nlm.nih.gov/pubmed/21887323
http://dx.doi.org/10.1371/journal.pone.0023804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161791/
https://www.ncbi.nlm.nih.gov/pubmed/21887323
http://dx.doi.org/10.1371/journal.pone.0023804

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