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Divalent Metal Ion Differentially Regulates the Sequential Nicking Reactions of the GIY-YIG Homing Endonuclease I-BmoI

Homing endonucleases are site-specific DNA endonucleases that function as mobile genetic elements by introducing double-strand breaks or nicks at defined locations. Of the major families of homing endonucleases, the modular GIY-YIG endonucleases are least understood in terms of mechanism. The GIY-YI...

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Detalles Bibliográficos
Autores principales:	Kleinstiver, Benjamin P., Bérubé-Janzen, Wesley, Fernandes, Andrew D., Edgell, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161791/ https://www.ncbi.nlm.nih.gov/pubmed/21887323 http://dx.doi.org/10.1371/journal.pone.0023804

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