Aconitase Regulation of Erythropoiesis Correlates with a Novel Licensing Function in Erythropoietin-Induced ERK Signaling

BACKGROUND: Erythroid development requires the action of erythropoietin (EPO) on committed progenitors to match red cell output to demand. In this process, iron acts as a critical cofactor, with iron deficiency blunting EPO-responsiveness of erythroid progenitors. Aconitase enzymes have recently bee...

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Detalles Bibliográficos
Autores principales: Talbot, Anne-Laure, Bullock, Grant C., Delehanty, Lorrie L., Sattler, Martin, Zhao, Zhizhuang Joe, Goldfarb, Adam N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161794/
https://www.ncbi.nlm.nih.gov/pubmed/21887333
http://dx.doi.org/10.1371/journal.pone.0023850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161794/
https://www.ncbi.nlm.nih.gov/pubmed/21887333
http://dx.doi.org/10.1371/journal.pone.0023850

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