Heterologous production of active ribonuclease inhibitor in Escherichia coli by redox state control and chaperonin coexpression

BACKGROUND: Eukaryotic Ribonuclease inhibitor (RI), belonging to the RNH1 family, is distinguished by unique features - a high sensitivity to oxidation due to the large number of reduced cysteins and a high hydrophobicity, which made most production approaches so far unsuccessful or resulted in very...

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Detalles Bibliográficos
Autores principales: Šiurkus, Juozas, Neubauer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161860/
https://www.ncbi.nlm.nih.gov/pubmed/21824411
http://dx.doi.org/10.1186/1475-2859-10-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161860/
https://www.ncbi.nlm.nih.gov/pubmed/21824411
http://dx.doi.org/10.1186/1475-2859-10-65

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