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The emphysematous lung is abnormally sensitive to TRAIL-mediated apoptosis

BACKGROUND: Alveolar apoptosis is increased in the emphysematous lung. However, mechanisms involved are not fully understood. Recently, we demonstrated that levels of TRAIL receptor 1 and 2, levels of p53, and Bax/Bcl-x(L )ratio were elevated in the lung of subjects with emphysema, despite smoking c...

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Detalles Bibliográficos
Autores principales: Morissette, Mathieu C, Parent, Julie, Milot, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161865/
https://www.ncbi.nlm.nih.gov/pubmed/21824395
http://dx.doi.org/10.1186/1465-9921-12-105