Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta)

BACKGROUND: Tafenoquine is an 8-aminoquinoline being developed for radical cure (blood and liver stage elimination) of Plasmodium vivax. During monotherapy treatment, the compound exhibits slow parasite and fever clearance times, and toxicity in glucose-6-phosphate dehydrogenase (G6PD) deficiency is...

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Detalles Bibliográficos
Autores principales: Dow, Geoffrey S, Gettayacamin, Montip, Hansukjariya, Pranee, Imerbsin, Rawiwan, Komcharoen, Srawuth, Sattabongkot, Jetsumon, Kyle, Dennis, Milhous, Wilbur, Cozens, Simon, Kenworthy, David, Miller, Anne, Veazey, Jim, Ohrt, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161915/
https://www.ncbi.nlm.nih.gov/pubmed/21801400
http://dx.doi.org/10.1186/1475-2875-10-212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161915/
https://www.ncbi.nlm.nih.gov/pubmed/21801400
http://dx.doi.org/10.1186/1475-2875-10-212

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