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The Steroid Catabolic Pathway of the Intracellular Pathogen Rhodococcus equi Is Important for Pathogenesis and a Target for Vaccine Development

Rhodococcus equi causes fatal pyogranulomatous pneumonia in foals and immunocompromised animals and humans. Despite its importance, there is currently no effective vaccine against the disease. The actinobacteria R. equi and the human pathogen Mycobacterium tuberculosis are related, and both cause pu...

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Detalles Bibliográficos
Autores principales: van der Geize, R., Grommen, A. W. F., Hessels, G. I., Jacobs, A. A. C., Dijkhuizen, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161971/
https://www.ncbi.nlm.nih.gov/pubmed/21901092
http://dx.doi.org/10.1371/journal.ppat.1002181