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Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration

The HIV/AIDS pandemic is a major global health threat and understanding the detailed molecular mechanisms of HIV replication is critical for the development of novel therapeutics. To replicate, HIV-1 must access the nucleus of infected cells and integrate into host chromosomes, however little is kno...

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Detalles Bibliográficos
Autores principales: Zhou, Lihong, Sokolskaja, Elena, Jolly, Clare, James, William, Cowley, Sally A., Fassati, Ariberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161976/
https://www.ncbi.nlm.nih.gov/pubmed/21901095
http://dx.doi.org/10.1371/journal.ppat.1002194